Sugar May Fuel Breast Cancer Growth

In a new study, scientists found that dietary sugar may fuel breast cancer growth. A typical diet may increase the risks of lung metastasis and breast cancer.

The investigation conducted by several researchers from the MD Anderson Center at the University of Texas explaining dietary sugar’s influence on an enzymatic signaling pathway. The enzymatic signaling pathway is known as 12 lipoxygenases, or 12-L.O.X. Professor Peiying Yang discussed the impact of sucrose consumption in mice. Discovering that ingesting comparable levels of a Western diet led to enhanced tumor extension and metastasis. Comparing to a diet without sugar intake. He adds that this was due to a prolonging expression of 12-LOX. And the presence of a fatty acid known as 12-HETE.

Lorenzo Cohen, co-author of the study, said that their research investigated the result of dietary sugar intakes on the mammary glands tumor growth in many mouse subjects. Cohen also said that they found out that fructose in sugar and corn syrup was the culprit. The sweet poison is responsible for developing 12-H.E.T.E. in breast tumors and lung metastasis.

Both authors also mentioned that it was a matter of public health priority to identify risk factors related to breast cancer. Identifying these factors was the primary objective of their research. Cohen stated in a press interview that their data suggests that sugar caused 12-L.O.X and 12-H.E.T.E production in tumor cells in the breast. This, in turn, may result in tumor’s growth.

The mice trial was designing to emulate a human response as closely as possible. Higher lung metastases were found to be evident in mice fed with a sugar-rich diet.

Identifying cancer risk factors is extremely necessary considering how people eat. They conclude that sugar consumption rate is a factor that must be taken into consideration. In the U.S., the staggering per capita sugar consumption has grown to over 100 lbs every year.

Consuming sugary beverages is also a main contributor to an obesity and heart disease epidemic. As well as cancer worldwide.

The study team thinks that the mechanism by which dietary fructose or sucrose induces breast tumor growth and metastasis requires further investigation. Special attention to the effect of 12-LOX pathways may also be the key.

Several trade groups and other experts involved the food and beverage industry argue that sugar and fructose. In general, are safe. They argue that as of today there’s no proof that fructose is any worse than any other sugars. As evidence of their position, they point out that fructose is containing in natural fruit, for example.

Breast Cancer